In the first Senate test for President Barack Obama's top domestic priority, Democrats unanimously backed a procedural motion to open debate over the opposition of 39 Republicans. Republican George Voinovich did not vote.
Democrats needed 60 votes to approve the motion in the 100-member Senate and had no margin for error -- they control exactly 60 votes.
The Democratic victory was assured earlier in the day when the party's last two holdouts, Blanche Lincoln and Mary Landrieu, said they would support the motion but would not commit to backing the final bill without changes.
"I believe that it is more important that we begin this debate to improve our nation's healthcare system for all Americans rather than just simply drop the issue and walk away," Lincoln said in a speech hours before the vote.
The debate will begin on Nov. 30 and is expected to last at least three weeks. The House of Representatives has passed its own version, and differences in the two would have to be reconciled in January before Obama could sign a final measure.
SOURCE: Reuters